AChE-IN-96
AChE-IN-96 (Compound 8a) is an AChE inhibitor, with an IC50 of 0.697 μM. AChE-IN-96 can be used for the study of neurodegenerative diseases such as Alzheimer's disease (AD) [1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(NC1=CC=C(C)C=C1C)CSC2=NN=C(COC3=CC=C4C=CC=CC4=C3)N2C5=CC=CC=C5
Molecular Formula
C29H26N4O2S
Molecular Weight
494.61
References & Citations
[1]Ayub M, et al. Design, Synthesis, and Computational Studies of Novel N- (Substituted phenyl) -3- (5- ((naphthalen-2-yloxy) methyl) -4-phenyl‑4H‑1,2,4-triazol-3-ylthio) acetamides as Potent Acetylcholinesterase Inhibitors. ACS Omega. 2025 Sep 29;10 (39) :45191-45203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
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