AB-22
AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis[1].
Product Specifications
CAS Number
1463913-43-0
UNSPSC
12352005
Target
Acetolactate Synthase (ALS) ; Endothelin-Converting Enzyme (ECE) ; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(NN(CCO)C1=CC(C(C)C)=C(C(C)=NN2C)C2=N1)NC3=CC(OCCC)=NC(Cl)=C3
Molecular Formula
C22H30ClN7O3
Molecular Weight
475.97
References & Citations
[1]Lee KT, et al. The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasis. J Microbiol. 2022;60 (4) :438-443.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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