ML301
ML301 is a small molecule G-protein agonist. ML301 can be inhibited by SR142948A with an IC50 of around 63 nM. ML301 fully competes for 125I-NT binding[1].
Product Specifications
CAS Number
[1531633-84-7]
UNSPSC
12352005
Target
GPR35
Related Pathways
GPCR/G Protein
Field of Research
Others
Smiles
CC(C)C[C@@H](C(O)=O)NC(C1=CN(C2=CC=NC3=C2C=CC(Cl)=C3)C(C4=C(C=CC=C4OC)OC)=N1)=O
Molecular Formula
C27H27ClN4O5
Molecular Weight
522.98
References & Citations
[1]Barak LS, et al., ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. ACS Chem Biol. 2016 Jul 15;11 (7) :1880-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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