ALV-05-077-01
ALV-05-077-01 is a BLC6/BLC6B degrader. ALV-05-077-01 depletes endogenous BCL6 levels in SuDHL4 cells (high BCL6 expression) and BCL6B levels in KYO1 cells (high BCL6B expression) . ALV-05-077-01 can be used for the study of hematological malignancies[1].
Product Specifications
CAS Number
[2438125-72-3]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C1C=C(C(N1C2C(NC(CC2)=O)=O)=O)NC3=CC=CC(CCC(NC4=CC=CC(C(F)(F)F)=C4)=O)=C3
Molecular Formula
C25H21F3N4O5
Molecular Weight
514.45
References & Citations
[1]Słabicki M, et al. Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation. Mol Cell. 2025 Aug 21;85 (16) :3184-3201.e14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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