ARCA

ARCA (Anti-Reverse cap analog) is a 5′- cap analogue. ARCA caps mRNA. ARCA can be used in protein expression studies[1].

Product Specifications

CAS Number

[400806-46-4]

Product Name Alternative

Anti-Reverse cap analog; m2 7,3′O GpppG

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

O=P(O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O1)OP(OP(OC[C@@H]4[C@@H](OC)[C@@H](O)[C@H](N5C(NC(N)=N6)=C([N+](C)=C5)C6=O)O4)([O-])=O)(O)=O

Molecular Formula

C22H31N10O18P3

Molecular Weight

816.46

References & Citations

[1]Kowalska J, et al. Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes. Nucleic Acids Res. 2014;42 (16) :10245-64.