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V1b Receptor antagonist-1

V1b receptor antagonist-1 is a potent, selective and brain-penetrant vasopressin 1b (V1b) receptor antagonist. V1b receptor antagonist-1 exhibits anti-depressant activity. V1b receptor antagonist-1 can be used for the research of neurological disease, such as depression[1].

Product Specifications

CAS Number

1056550-56-1

UNSPSC

12352005

Target

Vasopressin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

N#CC1=CC=C2C(C(C3=CC(OC)=CC=C3OCC)(N4CCN(CC4)C5=CC=NC=C5)C(N2S(=O)(C6=CC=CC7=CC=CN=C76)=O)=O)=C1

Molecular Formula

C36H32N6O5S

Molecular Weight

660.74

References & Citations

[1]Geneste H, et al. Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists. Bioorg Med Chem Lett. 2018 Oct 15;28 (19) :3260-3264.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

V1b Receptor

Frequently Asked Questions

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