Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine
Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine can be used for synthesizing PROTAC CDK4/6/9 degrader 1.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C(CC1)N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCN4C(CN(CC5)CCC5CN(CC6)CCN6C(OC(C)(C)C)=O)=O)=O)NC1=O
Molecular Formula
C34H47N7O7
Molecular Weight
665.78
References & Citations
[1]Hu H, et al. Translational Research on the Oral Delivery of the Cytotoxic PROTAC Molecule via Tumor-Targeting Prodrug Strategy for Triple-Negative Breast Cancer Treatment. J Med Chem. 2025 Oct 9;68 (19) :20464-20486.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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