KIF18A-IN-17
KIF18A-IN-17 (Example 37A) is a KIF18A inhibitor with racemic form with an IC50 of 48 nM. KIF18A-IN-17 exhibits anti-proliferative activity against HT29 cells. KIF18A-IN-17 can be used for the study of cancers such as breast cancer and ovarian cancer[1].
Product Specifications
UNSPSC
12352005
Target
Kinesin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
FC1(F)CN(C2=CC=CC(NC(C3=CC=C(NS(=O)(CCO)=O)C=C34)=O)=N2)CC1OCCC5CCN4CC5
Molecular Formula
C25H31F2N5O5S
Molecular Weight
551.61
References & Citations
[1]Dong DING, et al, Macrocyclic kif18a inhibitors and their use thereof, WO2025190888A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
126971 100 µg
FPR2 (N-formyl Peptide Receptor 2, FMLP-related Receptor I, FMLP-R-I, Formyl Peptide Receptor-like 1, HM63, Lipoxin A4 Receptor, LXA4 Receptor, RFP, FPRH1, FPRL1, LXA4R)
Sign In for Pricing
View Details 