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KIF18A-IN-17

KIF18A-IN-17 (Example 37A) is a KIF18A inhibitor with racemic form with an IC50 of 48 nM. KIF18A-IN-17 exhibits anti-proliferative activity against HT29 cells. KIF18A-IN-17 can be used for the study of cancers such as breast cancer and ovarian cancer[1].

Product Specifications

UNSPSC

12352005

Target

Kinesin

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

FC1(F)CN(C2=CC=CC(NC(C3=CC=C(NS(=O)(CCO)=O)C=C34)=O)=N2)CC1OCCC5CCN4CC5

Molecular Formula

C25H31F2N5O5S

Molecular Weight

551.61

References & Citations

[1]Dong DING, et al, Macrocyclic kif18a inhibitors and their use thereof, WO2025190888A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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