DDO3602
DDO3602 is a PARP1 HEMTAC degradation agent mediated by HSP90. DDO3602 has good anti-tumor activity and tumor selectivity. DDO3602 induces G2/M phase arrest, DNA damage, and inhibits cell migration by degrading PARP1 in MCF-7 cells (IC50 = 187 nM) . DDO3602 can be used for research on cancer such as breast cancer. (Pink: PARP1 Ligand (HY-75706) ; Blue: HSP90 Ligand (HY-179203) ; Black: Linker (HY-W015300) ) [1]
Product Specifications
UNSPSC
12352005
Target
HSP; PARP; PROTACs
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
CC(C1=C(C=C(C(C(N2CC3=C(C2)C=CC(CN4CCN(CC4)C(CCCCCCC(N5CCN(C(C6=CC(CC7=NNC(C8=CC=CC=C87)=O)=CC=C6F)=O)CC5)=O)=O)=C3)=O)=C1)O)O)C
Molecular Formula
C51H58FN7O7
Molecular Weight
900.05
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Aquaporin 8 (AQP8) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C10]
Lentiviral human CARM1 sgRNA gene knockout kit - Lentiviral human CARM1 sgRNA gene knockout kit (100)