BRM/BRG1 ATP-IN-7
BRM/BRG1 ATP-IN-7 (Compound Cpd69) is a selective dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with IC50 values of 12 nM and 8 nM, respectively. BRM/BRG1 ATP-IN-7 is promising for research of BRM/BRG1-dependent cancers (e.g., non-small cell lung cancer, Ewing sarcoma) and virus-associated diseases (e.g., HPV infection) [1].
Product Specifications
CAS Number
[2468048-19-1]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer; Infection
Smiles
O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](CO)C(NC2=NC(C3=CC(C4=CC=NC=C4)=CC=C3)=CS2)=O
Molecular Formula
C23H21N5O5S2
Molecular Weight
511.57
References & Citations
[1]Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1. 2020-08-06.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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