SH6
SH6 is a transcription factor ZBTB7A degrader. SH6 is promising for research of β-hemoglobinopathies such as sickle cell disease (SCD) and β-thalassemia[1].
Product Specifications
CAS Number
[2619408-35-2]
UNSPSC
12352005
Target
Histone Acetyltransferase
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(NC1=C(N)C=C(Cl)C=C1)/C=C/C2=C(NC3=CC(OC)=C(OC)C(OC)=C3)N=CC=C2
Molecular Formula
C23H23ClN4O4
Molecular Weight
454.91
References & Citations
[1]Liu J, et al. Discovery of A Small Molecule non-IMiD Degrader of ZBTB7A for the Treatment of β-beta-hemoglobinopathies[J]. bioRxiv, 2025: 2025.09. 17.676148.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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