BRM/BRG1 ATP-IN-6
BRM/BRG1 ATP-IN-6 (Compound 105) is a BRG1/BRM inhibitor. BRM/BRG1 ATP-IN-6 acts on the BAF complex, which is involved in chromatin regulation and gene expression via ATP-dependent chromatin remodeling. BRM/BRG1 ATP-IN-6 demonstrates anti-tumor potential, particularly in cancers associated with BAF complex disorders[1].
Product Specifications
CAS Number
[2468049-60-5]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CN(C=C1)S(C)(=O)=O)NCC(NC2=NC(C3=CC(CO[C@@H]4CC[C@H](CC4)O)=CC=C3)=CS2)=O
Molecular Formula
C24H28N4O6S2
Molecular Weight
532.63
References & Citations
[1]VASWANI, et al. COMPOUNDS AND USES THEREOF. WO 2020/160180A1. World Intellectual Property Organization (WIPO) . 06 August 2020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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