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Anti-MRSA agent 36

Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL) . Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models[1].

Product Specifications

CAS Number

3096122-10-7

UNSPSC

12352005

Target

Bacterial; Reactive Oxygen Species (ROS)

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Infection

Smiles

CCCCCCNC(C[N+]1=CC=C(SCCCCCOC2=C(O3)C(C=CC3=O)=CC4=C2OC=C4)C=C1)=O.[Br-]

Molecular Formula

C29H35BrN2O5S

Molecular Weight

603.57

References & Citations

[1]Renzi G, et al. Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis-induced tumor cell death. Eur J Med Chem. 2025 Dec 15;300:118107.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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