F0840-0093
F0840-0093 is a highly selective estrogen receptor α (ERα) degrader. F0840-0093 exhibits potent antiproliferative activity against T47D cells with an IC50 value of 4.65 μM. F0840-0093 is promising for research of estrogen receptor-positive (ER+) breast cancer[1].
Product Specifications
CAS Number
503429-76-3
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=C1C2=CC=CC3=C2C(C(N1CCN4CCN(CC4)C[C@@H](COCC5=CC=C(C=C5)Cl)O)=O)=CC=C3
Molecular Formula
C28H30ClN3O4
Molecular Weight
508.01
References & Citations
[1]Chen M, et al. Identification of novel selective estrogen receptor degraders (SERD) via physics-based and deep-learning-based virtual screening and Bioassys. Bioorg Chem. 2025 Oct;165:109011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP322056M 100 µg
PIB5PA (INPP5J) (NM_001002837) Human Recombinant Protein
Sign In for Pricing
View Details 
TP306579L 1 mg
Exodus 2 (CCL21) (NM_002989) Human Recombinant Protein
Sign In for Pricing
View Details 