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Orthopoxviruses-IN-1

Orthopoxviruses-IN-1 (Compound 4) is a potent p37 protein inhibitor (IC50= 0.017 µM against Vaccinia virus (VACV) ) . Orthopoxviruses-IN-1 is promising for research of orthopoxvirus-related diseases, including variola virus (smallpox) and monkeypox[1].

Product Specifications

CAS Number

[3089950-34-2]

UNSPSC

12352005

Target

Orthopoxvirus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1ON=C(N1C2=CC=C(C=C2)[N+]([O-])=O)C3=CC=C(C=C3)C(F)(F)F

Molecular Formula

C15H8F3N3O4

Molecular Weight

351.24

References & Citations

[1]Semenov A V, et al. Expanding the antiviral arsenal: N-arylated 1, 2, 4-oxadiazol-5 (4H) -ones show high activity against orthopoxviruses[J]. European Journal of Medicinal Chemistry, 2025: 118124.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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