Flt-3-IN-1
Flt-3-IN-1 is a potent FLT-3 inhibitor with an IC50 of 0.91 μM. Flt-3-IN-1 can cause leukemia cells G1 phase arrest and induce apoptosis. Flt-3-IN-1 can be used for the research of cancer, such as leukemia[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; FLT3
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=CC=C(C2=NN=C(SCC(NC3=CC=C(NC4=CC(CC(C)(C)C4)=O)C=C3)=O)O2)C=C1
Molecular Formula
C24H23ClN4O3S
Molecular Weight
482.98
References & Citations
[1]Abdelhameid MK, et al. Design, synthesis and biological screening of some diaryl acetamide derivatives as potential cytotoxic agents on HL-60 (TB) cell line. Bioorg Chem. 2025 Oct;165:108999.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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