Bastadins-5
Bastadins-5 is a potent stabilizer for the open state of RYR1. Bastadins-5 enhances Ca2+-induced Ca2+ release. Bastadins-5 can be used in research on central nuclear disease and malignant hypothermia[1].
Product Specifications
CAS Number
79067-75-7
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
BrC1=C(O)C2=CC(C/C(C(NCCC3=CC(Br)=C(OC4=C(C(Br)=CC(CCNC(/C(CC5=CC(Br)=C(C(Br)=C5)O2)=N/O)=O)=C4)O)C=C3)=O)=N/O)=C1
Molecular Formula
C34H27Br5N4O8
Molecular Weight
1019.12
References & Citations
[1]Franklin MA, et al. Structure-activity of Bastadins from the marine sponge Ianthella basta. Modulators of the RYR1 Ca2+ channel. Bioorg Med Chem Lett. 2025 Jun 1;121:130165.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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