Bastadins-5
Bastadins-5 is a potent stabilizer for the open state of RYR1. Bastadins-5 enhances Ca2+-induced Ca2+ release. Bastadins-5 can be used in research on central nuclear disease and malignant hypothermia[1].
Product Specifications
CAS Number
79067-75-7
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
BrC1=C(O)C2=CC(C/C(C(NCCC3=CC(Br)=C(OC4=C(C(Br)=CC(CCNC(/C(CC5=CC(Br)=C(C(Br)=C5)O2)=N/O)=O)=C4)O)C=C3)=O)=N/O)=C1
Molecular Formula
C34H27Br5N4O8
Molecular Weight
1019.12
References & Citations
[1]Franklin MA, et al. Structure-activity of Bastadins from the marine sponge Ianthella basta. Modulators of the RYR1 Ca2+ channel. Bioorg Med Chem Lett. 2025 Jun 1;121:130165.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2004305 3x 1.0 µg
RPS2P53 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 