SARS-CoV-2 Mpro-IN-48
SARS-CoV-2 Mpro-IN-48 is a potent SARS-CoV-2 main protease inhibitor with an IC50 of 21.1 nM. SARS-CoV-2 Mpro-IN-48 exhibits potent antiviral activity against the SARS-CoV-2 JN.1 variant. SARS-CoV-2 Mpro-IN-48 can be used for the research of infection, such as COVID-19[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C1N(C2=CC(C)=CN=C2)C(C(C3=CC=C(F)C(Cl)=C3)=C(C4=CC=C(F)C=C4)N1)=O
Molecular Formula
C22H14ClF2N3O2
Molecular Weight
425.82
References & Citations
[1]Rao Z, et al. Discovery and evaluation of pyrimidine-2,4-dione derivatives as novel SARS-CoV-2 Mpro inhibitors with antiviral effect. Bioorg Chem. 2025 Oct;165:109026.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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