GnRH-R antagonist-3
GnRH-R antagonist-3 (Compound 37) is a Gonadotropin releasing hormone receptor (GnRH-R) antagonist with IC50s of 94 and 275 nM for rat and human GnRH-R, respectively. GnRH-R antagonist-3 can be used for hormone dependent diseases such as endometriosis, breast and prostate cancer research[1].
Product Specifications
CAS Number
[666852-12-6]
UNSPSC
12352005
Target
GnRH Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Smiles
O=C(N1CCOCC1)NCC2CCN(CC2)CCC3=C(C4=CC(C)=CC(C)=C4)NC5=C3C=C(C(C)(C)C(N6C7CCC6CC7)=O)S5
Molecular Formula
C37H51N5O3S
Molecular Weight
645.90
References & Citations
[1]Arnould JC, et al. Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor. Bioorg Med Chem Lett. 2007 Dec 1;17 (23) :6448-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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