GSTO1-IN-4
GSTO1-IN-4 is a selective, potent GSTO1-1 inhibitor (IC50 = 0.04 μM; KI = 0.16 μM) . GSTO1-IN-4 shows low inhibition to GSTO2-2, GSTA1-1 and GSTP1-1. GSTO1-IN-4 shows a capacity to attenuate inflammation in mice and to significantly enhance the cytotoxicity of Cisplatin (HY-17394) . GSTO1-IN-4 can be used for the study of inflammation and breast cancer[1].
Product Specifications
CAS Number
[158890-33-6]
UNSPSC
12352005
Target
Glutathione S-transferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N1CCC(CC1)CCCC2=CC=CC=C2)CCl
Molecular Formula
C16H22ClNO
Molecular Weight
279.80
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items