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GSTO1-IN-4

GSTO1-IN-4 is a selective, potent GSTO1-1 inhibitor (IC50 = 0.04 μM; KI = 0.16 μM) . GSTO1-IN-4 shows low inhibition to GSTO2-2, GSTA1-1 and GSTP1-1. GSTO1-IN-4 shows a capacity to attenuate inflammation in mice and to significantly enhance the cytotoxicity of Cisplatin (HY-17394) . GSTO1-IN-4 can be used for the study of inflammation and breast cancer[1].

Product Specifications

CAS Number

[158890-33-6]

UNSPSC

12352005

Target

Glutathione S-transferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(N1CCC(CC1)CCCC2=CC=CC=C2)CCl

Molecular Formula

C16H22ClNO

Molecular Weight

279.80

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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