PAC/NP-IN-1
PAC/NP-IN-1 (Compound 30) is a dual-target anti-influenza agent that specifically binds to nucleoprotein (NP) and the C-terminal domain of PA protein (PAc) . PAC/NP-IN-1 inhibits influenza A virus A/WSN/33 (H1N1) (EC50 = 3.63 μM, IC50 = 3.08 μM) . PAC/NP-IN-1 can be used for the study of influenza infection[1].
Product Specifications
UNSPSC
12352005
Target
Influenza Virus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=C(NC2=NC=NC3=CC=CC=C32)C=CC=C1)NCCN4CCN(C5=C(C)C=C(C)C=C5)CC4
Molecular Formula
C29H32N6O
Molecular Weight
480.60
References & Citations
[1]Zhang C, et al. Quinazoline-based dual-target inhibitors disrupt influenza virus RNP complex: Rational design, synthesis and mechanistic validation of potent anti-influenza agents. Eur J Med Chem. 2025 Sep 21;301:118185.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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