PAD-IN-4
PAD-IN-4 is a potent PAD inhibitor (PAD 1/4, IC50 = 0.273/0.24 μM) . PAD-IN-4 shows no significant cytotoxicity against A549 or MDA-MB-231 cells. PAD-IN-4 can be used for the study of cancer and autoimmune diseases[1].
Product Specifications
UNSPSC
12352005
Target
Protein Arginine Deiminase
Related Pathways
Epigenetics
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N[C@@H](CCCNC(CCl)=N)C(NCC1=CC=CC=C1)=O)C2=CC=C3C=C(O)C=CC3=C2
Molecular Formula
C25H27ClN4O3
Molecular Weight
466.96
References & Citations
[1]Jia Y, et al. Discovery of highly potent naphthalene/quinoline-based PAD inhibitors: Structure-activity relationship, selectivity, and cytotoxicity. Eur J Med Chem. 2025 Oct 15;296:117830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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