ZZ7-23-022
ZZ7-23-022 (ZZ7) is a selective BRD9 molecule glue degrader. ZZ7-23-022 effectively degrades BRD9 in synovial sarcoma cells, but does not affect cardiomyocytes. ZZ7-23-022 can be used for the research of cancer[1].
Product Specifications
Product Name Alternative
ZZ7
UNSPSC
12352005
Target
Epigenetic Reader Domain; Molecular Glues
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(N1CCN(C2COC2)CC1)(C)/C=C(C(N3CCN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)CC3)=O)\C#N
Molecular Formula
C36H45N7O5
Molecular Weight
655.79
References & Citations
[1]Byun WS, et al. Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes. J Am Chem Soc. 2025 Oct 1;147 (39) :35481-35492.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD9
Curated Selection
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