SGC-CK1γ-1
SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection[1].
Product Specifications
UNSPSC
12352005
Target
CMV; LDLR; Wnt
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Stem Cell/Wnt
Field of Research
Infection
Smiles
N#CC1=CC=C2C(N=C(NC3=CC=C(N4CCOCC4)C(Cl)=C3)N2)=C1
Molecular Formula
C18H16ClN5O
Molecular Weight
353.81
References & Citations
[1]Capener JL, et al. Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily. bioRxiv [Preprint]. 2025 Sep 16:2025.09.10.675406.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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