HDAC6-IN-66
HDAC6-IN-66 is a potent and selective histone deacetylase (HDAC) 6 inhibitor with an IC50 of 1.8 nM. HDAC6-IN-66 induces α-tubulin acetylation over histone H3. HDAC6-IN-66 can be used for the research of cancer[1].
Product Specifications
CAS Number
3095060-23-1
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NO)C1=CC=C(CN2N=C(C3=CC=CO3)C4=C2C=CC=C4)C=C1
Molecular Formula
C19H15N3O3
Molecular Weight
333.34
References & Citations
[1]Ali KH, et al. Design, synthesis, and biological evaluation of indazole-based histone deacetylase 6 inhibitors. Eur J Med Chem. 2025 Oct 5;295:117785.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC3; HDAC6
Frequently Asked Questions
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