ProAX
ProAX is an AXP prodrug which enhances intracellular ATP levels without inducing cytotoxicity. ProAX can be metabolized by intracellular enzymes such as esterases and phosphoamidases, resulting in the conversion to AMP, ADP, and ATP. ProAX has potential applications in the research of bioenergetic-molecule therapeutics[1].
Product Specifications
CAS Number
2978687-02-2
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
98.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1CO[P@](OC4=CC=CC=C4)(N[C@@H](C)C(OCC(CC)CC)=O)=O
Molecular Formula
C25H35N6O8P
Molecular Weight
578.55
References & Citations
[1]Anada T, et al. A Nucleic Acid Prodrug That Activates Mitochondrial Respiration, Promotes Stress Resilience, and Prolongs Lifespan. J Am Chem Soc. 2025 Jun 25;147 (25) :22161-22175.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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