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ProAX

ProAX is an AXP prodrug which enhances intracellular ATP levels without inducing cytotoxicity. ProAX can be metabolized by intracellular enzymes such as esterases and phosphoamidases, resulting in the conversion to AMP, ADP, and ATP. ProAX has potential applications in the research of bioenergetic-molecule therapeutics[1].

Product Specifications

CAS Number

[2978687-02-2]

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

98.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1CO[P@](OC4=CC=CC=C4)(N[C@@H](C)C(OCC(CC)CC)=O)=O

Molecular Formula

C25H35N6O8P

Molecular Weight

578.55

References & Citations

[1]Anada T, et al. A Nucleic Acid Prodrug That Activates Mitochondrial Respiration, Promotes Stress Resilience, and Prolongs Lifespan. J Am Chem Soc. 2025 Jun 25;147 (25) :22161-22175.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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