UNC10415667

UNC10415667 is a NSD2 degrader, with a DC50 values of 460 nM. UNC10415667 can be used for the study of cancers driven by NSD2 overexpression or dysregulation, such as multiple myeloma, acute lymphocytic leukemia, and prostate cancer[1].

Product Specifications

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O=C(C1=CC=C(N2)C(OCC2=O)=C1)N(C3CC3)CC4=CC=C(C(NC5=CC6=C(CN(C(C7=CC=C(C=O)C=C7)=O)CC6)C=C5)=O)C=C4

Molecular Formula

C37H32N4O6

Molecular Weight

628.67

References & Citations

[1]Robertson, K. C., Amann, S. J., Liu, T., et al. Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22. bioRxiv. 2025

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NSD2/MMSET/WHSC1

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