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LRH-0003

LRH-0003 is an inhibitor of the Macrodomain 1 (Mac1) of nonstructural protein 3 (NSP3) from SARS-CoV-2, with an IC50 value of 1.7 μM. LRH-0003 can be used for the research antiviral infection targeting SARS-CoV-2[1].

Product Specifications

CAS Number

2871220-06-1

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1N(CCC1)NC2=NC=NC3=C2C4=CC=C(F)C=C4N3

Molecular Formula

C14H12FN5O

Molecular Weight

285.28

References & Citations

[1]Fuqiang Ban, et al. Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space. Posted September 09, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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