LRH-0003
LRH-0003 is an inhibitor of the Macrodomain 1 (Mac1) of nonstructural protein 3 (NSP3) from SARS-CoV-2, with an IC50 value of 1.7 μM. LRH-0003 can be used for the research antiviral infection targeting SARS-CoV-2[1].
Product Specifications
CAS Number
[2871220-06-1]
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1N(CCC1)NC2=NC=NC3=C2C4=CC=C(F)C=C4N3
Molecular Formula
C14H12FN5O
Molecular Weight
285.28
References & Citations
[1]Fuqiang Ban, et al. Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space. Posted September 09, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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