Exatecan analog 38
Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research[1].
Product Specifications
CAS Number
[2766214-00-8]
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C([C@H]1C[C@@H](C1)OCNC(CN)=O)N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73
Molecular Formula
C32H34FN5O7
Molecular Weight
619.64
References & Citations
[1]Yu Zhang, et al. Antitumor compound, and preparation method therefor and use thereof. WO2022068878.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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