EGFR ligand-18
EGFR ligand-18 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC EGFR degrader 16. PROTAC EGFR degrader 16 is a potent EGFR PROTAC degrader with anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
EGFR; Ligands for Target Protein for PROTAC
Related Pathways
JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=NC=CS1)C(C2=C(CCC3)N3C=N2)N(CC4=C5C=C(C6=CC=CC=C6)C=C4F)C5=O
Molecular Formula
C25H20FN5O2S
Molecular Weight
473.52
References & Citations
[1]Christopher G, et al. EGFR DEGRADERS TO TREAT CANCER METASTASIS TO THE BRAIN OR CNS CROSS-REFERENCE TO RELATED APPLICATIONS. WO2022251539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400633-500 1x 500 µL
Von Willebrand Factor (3E2D10), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880181-500 1x 500 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940352-100 1x 100 µL
CD31 / PECAM-1 (158-2B3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details