EGFR Ligand-Linker Conjugates 4

EGFR Ligand-Linker Conjugates 4 is a conjugate of the EGFR ligand (HY-178313) and the linker. EGFR Ligand-Linker Conjugates 4 can be used for synthesizing PROTAC EGFR degrader 16 (HY-178242) [1].

Product Specifications

CAS Number

[2654824-18-5]

UNSPSC

12352005

Target

EGFR; Target Protein Ligand-Linker Conjugates

Related Pathways

JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C1C2=C(CN1C(C3=C(CCC4)N4C=N3)C(NC5=NC=CS5)=O)C(F)=CC(C6=CC=C(N7CC8(C7)CNC8)C=C6)=C2

Molecular Formula

C30H28FN7O2S

Molecular Weight

569.65

References & Citations

[1]Christopher G, et al. EGFR DEGRADERS TO TREAT CANCER METASTASIS TO THE BRAIN OR CNS CROSS-REFERENCE TO RELATED APPLICATIONS. WO2022251539. 2022-05-26