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MC-Gly-Gly-Phe-Exatecan analog 38

MC-Gly-Gly-Phe-Exatecan analog 38 (Compound L-II-4) is part of an antibody-drug conjugate (ADC), consisting of an ADC toxicant molecule and an ADC linker. MC-Gly-Gly-Phe-Exatecan analog 38 can be used to synthesize ADCs (such as ADC-II-15 and ADC-III-13) . MC-Gly-Gly-Phe-Exatecan analog 38 can also be used in cancer research (ADC Cytotoxin: HY-178315, ADC Linker: HY-44235) [1].

Product Specifications

CAS Number

[2766214-01-9]

UNSPSC

12352005

Target

Drug Intermediate; Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Cancer

Smiles

O=C([C@H]1C[C@@H](C1)OCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95

Molecular Formula

C55H60FN9O13

Molecular Weight

1074.12

References & Citations

[1]Zhang, et al. Antitumor compound, and preparation method therefor and use thereof. WO2022068878A1. WIPO (PCT) . 2021-09-29.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Curated Selection

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