TS-IN-7
TS-IN-7 (Compound 6) is a thymidylate synthase (TS) inhibitor with an IC50 of 39 nM. TS-IN-7 can be used for the study of cancer chemotherapy[1].
Product Specifications
CAS Number
150585-99-2
UNSPSC
12352005
Target
Thymidylate Synthase
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C1=CC=C(C=C1)C(N[C@H](C(O)=O)CCC(O)=O)=O)C2=CNC(NC(N)=N3)=C2C3=O
Molecular Formula
C20H21N5O6
Molecular Weight
427.41
References & Citations
[1]Aso K, et al. Pyrrolo[2,3-d]pyrimidine thymidylate synthase inhibitors: design and synthesis of one-carbon bridge derivatives. Chem Pharm Bull (Tokyo) . 2001 Oct;49 (10) :1280-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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