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TS-IN-7

TS-IN-7 (Compound 6) is a thymidylate synthase (TS) inhibitor with an IC50 of 39 nM. TS-IN-7 can be used for the study of cancer chemotherapy[1].

Product Specifications

CAS Number

150585-99-2

UNSPSC

12352005

Target

Thymidylate Synthase

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(C1=CC=C(C=C1)C(N[C@H](C(O)=O)CCC(O)=O)=O)C2=CNC(NC(N)=N3)=C2C3=O

Molecular Formula

C20H21N5O6

Molecular Weight

427.41

References & Citations

[1]Aso K, et al. Pyrrolo[2,3-d]pyrimidine thymidylate synthase inhibitors: design and synthesis of one-carbon bridge derivatives. Chem Pharm Bull (Tokyo) . 2001 Oct;49 (10) :1280-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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