TNF-α-IN-27
TNF-α-IN-27 (Compound 1) is a TNF-α inhibitor with inhibition rate of 64% at 10 μM. TNF-α-IN-27 can be used for the researches of inflammation and immunology, such as asthma[1].
Product Specifications
CAS Number
340307-20-2
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C(Cl)C=C(C2=CC=C(/C=C3C(NC(N(C4=CC=CC(C)=C4)C\3=O)=O)=O)O2)C=C1)O
Molecular Formula
C23H15ClN2O6
Molecular Weight
450.83
References & Citations
[1]Choi H, et al. Discovery of the inhibitors of tumor necrosis factor alpha with structure-based virtual screening. Bioorg Med Chem Lett. 2010 Nov 1;20 (21) :6195-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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