Avitinib-methyl

Avitinib-methyl is the metabolite of Avitinib (HY-19816) [1].

Product Specifications

CAS Number

[2093388-26-0]

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(CC)NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C(F)=C3)=NC5=C2C=CN5)=CC=C1

Molecular Formula

C26H28FN7O2

Molecular Weight

489.54

References & Citations

[1]Wang W, et al. Development of an UPLC-MS/MS method for quantification of Avitinib (AC0010) and its five metabolites in human cerebrospinal fluid: Application to a study of the blood-brain barrier penetration rate of non-small cell lung cancer patients. J Pharm Biomed Anal. 2017 May 30;139:205-214.