Avitinib-methyl
Avitinib-methyl is the metabolite of Avitinib (HY-19816) [1].
Product Specifications
CAS Number
[2093388-26-0]
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CC)NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C(F)=C3)=NC5=C2C=CN5)=CC=C1
Molecular Formula
C26H28FN7O2
Molecular Weight
489.54
References & Citations
[1]Wang W, et al. Development of an UPLC-MS/MS method for quantification of Avitinib (AC0010) and its five metabolites in human cerebrospinal fluid: Application to a study of the blood-brain barrier penetration rate of non-small cell lung cancer patients. J Pharm Biomed Anal. 2017 May 30;139:205-214.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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