Factor B-IN-7
Factor B-IN-7 (Compound (I) ) is a selective Factor B inhibitor. Factor B-IN-7 inhibits Factor B-C3b interaction to suppress complement hyperactivation. Factor B-IN-7 is promising for research of paroxysmal nocturnal hemoglobinuria (PNH), C3 glomerulopathy, and age-related macular degeneration (AMD) associated with complement-mediated diseases[1].
Product Specifications
UNSPSC
12352005
Target
Complement System
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
COC1=C(C2=C(C(C)=C1)NC=C2)CN3CCC4(C[C@]35CCC6=C5C=CC(C(O)=O)=C6)CC(F)(C4)F
Molecular Formula
C28H30F2N2O3
Molecular Weight
480.55
References & Citations
[1]Chen JY, et al. Crystal form of multi-membered spiro compound, and preparation method therefor and medical use thereof. WO2025185736A1. 2025-10-02.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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