Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol
Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol (Example 9) is a conjugate of the ADC toxic molecule and the linker, where the toxic molecule part is Hydrotecan , and the linker part is Mc-Glu (D-Glucamine) -val-ala (HY-178309).
Product Specifications
CAS Number
2694026-77-0
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
O=C1N2C(C(C(C2)=CC3=C4CCCCOCNC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(CCCCCN5C(C=CC5=O)=O)=O)CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=NC3=CC(F)=C4C)=CC6=C1COC([C@]6(O)CC)=O
Molecular Formula
C55H73FN8O17
Molecular Weight
1137.21
References & Citations
[1]Wei Li, et al. Auristatin derivatives and conjugates thereof. WO2024023735A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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