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Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol

Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol (Example 9) is a conjugate of the ADC toxic molecule and the linker, where the toxic molecule part is Hydrotecan , and the linker part is Mc-Glu (D-Glucamine) -val-ala (HY-178309).

Product Specifications

CAS Number

2694026-77-0

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

O=C1N2C(C(C(C2)=CC3=C4CCCCOCNC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(CCCCCN5C(C=CC5=O)=O)=O)CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=NC3=CC(F)=C4C)=CC6=C1COC([C@]6(O)CC)=O

Molecular Formula

C55H73FN8O17

Molecular Weight

1137.21

References & Citations

[1]Wei Li, et al. Auristatin derivatives and conjugates thereof. WO2024023735A1.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Frequently Asked Questions

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