Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol
Hydrotecan-NH-L-Ala-L-Val-L-Gln (CO-C5-succinimide) -D-glucitol (Example 9) is a conjugate of the ADC toxic molecule and the linker, where the toxic molecule part is Hydrotecan (HY-164378), and the linker part is Mc-Glu (D-Glucamine) -val-ala (HY-178309) [1].
Product Specifications
CAS Number
[2694026-77-0]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
O=C1N2C(C(C(C2)=CC3=C4CCCCOCNC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(CCCCCN5C(C=CC5=O)=O)=O)CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=NC3=CC(F)=C4C)=CC6=C1COC([C@]6(O)CC)=O
Molecular Formula
C55H73FN8O17
Molecular Weight
1137.21
References & Citations
[1]Wei Li, et al. Auristatin derivatives and conjugates thereof. WO2024023735A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6362001-01 0.1 mL
USP50, ID (USP50, Inactive ubiquitin carboxyl-terminal hydrolase 50, Inactive ubiquitin-specific peptidase 50) (MaxLight 650)
Ask
View Details MBS6362001-02 5x 0.1 mL
USP50, ID (USP50, Inactive ubiquitin carboxyl-terminal hydrolase 50, Inactive ubiquitin-specific peptidase 50) (MaxLight 650)
Ask
View Details