PBD derivative-1
PBD derivative-1 (Compound 7-8) is a derivative of PBD, and PBD is the payload in antibody-drug conjugates (ADCs) . PBD derivative-1 can be used for the synthesis of ADCs.
Product Specifications
CAS Number
[2305851-17-4]
UNSPSC
12352005
Target
ADC Payload
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1N2CC3(CC3)C[C@@]2([H])C=NC4=CC(OCCCCCOC5=C(C=C6C(NC[C@@]7([H])N(C=C(C8=CC=C(C=C8)OC)C7)C6=O)=C5)OC)=C(OC)C=C41
Molecular Formula
C40H44N4O7
Molecular Weight
692.80
References & Citations
[1]Tsuchida, et al. Antibody-pyrrolobenzodiazepine derivative conjugate. WO2020196474A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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