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Thioxo-Dxd

Thioxo-Dxd is a Camptothecin derivative. thioxo-Dxd can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. thioxo-Dxd can be used for research on tumors with high HER2 or TROP2 expression[1].

Product Specifications

CAS Number

2806052-35-5

UNSPSC

12352005

Target

ADC Payload

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

OCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O

Molecular Formula

C26H24FN3O5S

Molecular Weight

509.55

References & Citations

[1]Li Ao, et al. Antitumor compound and use thereof. WO2022262789A1. 2022-12-22

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Frequently Asked Questions

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