Thioxo-Dxd
Thioxo-Dxd is a Camptothecin (HY-16560) derivative. thioxo-Dxd can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. thioxo-Dxd can be used for research on tumors with high HER2 or TROP2 expression[1].
Product Specifications
CAS Number
[2806052-35-5]
UNSPSC
12352005
Target
ADC Payload
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Molecular Formula
C26H24FN3O5S
Molecular Weight
509.55
References & Citations
[1]Li Ao, et al. Antitumor compound and use thereof. WO2022262789A1. 2022-12-22
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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