(R) -thioxo-Dxd
(R) -thioxo-Dxd is a Camptothecin derivative. (R) -thioxo-Dxd can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. (R) -thioxo-Dxd can be used for research on tumors with high HER2 or TROP2 expression[1].
Product Specifications
CAS Number
2806052-36-6
UNSPSC
12352005
Target
ADC Payload
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OCC(N[C@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Molecular Formula
C26H24FN3O5S
Molecular Weight
509.55
References & Citations
[1]Ao Li, et al. Ligand conjugate compounds as antitumor agents and their preparation, pharmaceutical compositions and use in the treatment of cancer. WO2022262789.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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