Rel- (1S,2R) -Dihydro bupropion
Rel- (1S,2R) -Dihydro bupropion is a metabolite of bupropion. rel- (1S,2R) -Dihydro bupropion can promote endogenous IL-10 production and inhibit Th1 cytokines (IL-12 and TNF-α) . rel- (1S,2R) -Dihydro bupropion can induce immune response transition from Th1 to Th2. rel- (1S,2R) -Dihydro bupropion can be used for research on inflammatory conditions[1].
Product Specifications
CAS Number
[102141-11-7]
UNSPSC
12352101
Target
Endogenous Metabolite; Interleukin Related; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
CC(C)(C)N[C@H](C)[C@H](C1=CC(Cl)=CC=C1)O
Molecular Formula
C13H20ClNO
Molecular Weight
241.76
References & Citations
[1]Robin Mark Bannister, et al. Treatment of Th-1 mediated inflammatory diseases using bupropion and metabolites thereof. WO2012056229.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-10; IL-12
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