CAT335
CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure[1].
Product Specifications
CAS Number
3032789-44-6
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1C=CC(N1C2=CC=C(C(NCC3=CC=C(C=C3Cl)Cl)=O)C=C2)=O
Molecular Formula
C18H12Cl2N2O3
Molecular Weight
375.21
References & Citations
[1]Adam R. RENSLO, et al. Covalent, chemogenetic activators for k2p potassium channels and uses thereof. WO2024064923A2. WIPO (PCT) . 2023-09-22. |[2]Deal PE, et al. Development of covalent chemogenetic K2P channel activators. Cell Chem Biol. 2024 Jul 18;31 (7) :1305-1323.e9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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