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ALK5-IN-85

ALK5-IN-85 (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 [1].

Product Specifications

CAS Number

2766583-86-0

UNSPSC

12352005

Target

TGF-β Receptor

Related Pathways

TGF-beta/Smad

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(C1=CC(NC(CN2N=C(C(C3=C4C=CC=CC4=NC=C3)=C2)C5=CC=CC(C)=N5)=O)=CC(F)=C1)OCCN6CCNCC6

Molecular Formula

C33H32FN7O3

Molecular Weight

593.65

References & Citations

[1]BOSSER ARTAL R, et al. 2- (3-pyridin-2-yl-4-quinolin-4-yl-pyrazol-1-yl) -acetamide derivatives as inhibitors of transforming growth factor-beta receptor i/alk5. WO2022069509A1. 2022-04-07.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ALK5

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